FDA Authorizes Changes to Simplify Use of Bivalent mRNA COVID-19 Vaccines
Agency updates emergency use authorization for the Moderna and Pfizer-BioNTech COVID-19 vaccinations, which are no longer authorized for used in the United States.
Study: Individuals With HIV Have Higher Risk of Depression, Suicide
The risk is particularly high in the first 2 years after an HIV diagnosis.
FDA Grants EUA for Vilobelimab for Treatment of Critically Ill Patients With COVID-19
This drug is the first to control complement factor C5a, which is a protein that plays a significant but potentially harmful role in the body's immune response.
FDA Approves Rezafungin Injection for the Treatment of Candidemia, Invasive Candidiasis
Rezafungin (Rezzayo; Cidara Therapeutics Inc, Melinta Therapeutics LLC) is the first new treatment option approved for individuals with candidemia and invasive candidiasis in more than a decade.
Study: Single Dose of Vaccine May Protect Older Adults from RSV-Related Infection
Findings from the ongoing Adult Respiratory Syncytial Virus phase 3 trial suggest RSVPreF3 OA vaccine is effective and safe for individuals aged 60 years and older.
Research Finds Impact of Chronic Pain on Daily Life is Biggest Threat to Mental Health
Persistently pursuing valued goals and adjusting those goals in response to setbacks or obstacles may help explain how some individuals with chronic pain maintain their mental wellbeing.
Experts Debate Approaches to Oral Anticoagulation After Ablation
Findings from the AFFIRM trial found increased risks after stopping oral anticoagulant therapy after rhythm control, and the same is true for stopping treatment with oral anticoagulants after successful ablation.
Is It Too Late to Get a Flu Shot?
Ideally, older patients receive vaccinations by October, but disease activity often peaks in February or March.
Convenience, Effectiveness Prove Significant Attributes in Vaccine Uptake Decisions
US adults have a slightly stronger preference for fewer adverse events in relation to pediatric COVID-19 vaccination, study results show.
Migraine Associated With Preterm Birth, Preeclampsia Complications During Pregnancy
Migraine could be considered a clinical marker of increased obstetric risk in pregnant women.
States With Legal Medical, Recreational Cannabis Policies Do Not Have Significantly Higher Rate of Psychosis-Related Outcomes
This is the largest known study to consider medical and recreational cannabis policies with US psychosis-related health care claims.
FDA Accepts sNDA for Jardiance as Potential Treatment for Chronic Kidney Disease
The supplemental new drug application is based on results from a landmark phase 3 trial showing that empagliflozin tablets provided meaningful results.
FDA Approves Adacel Vaccine During Pregnancy to Protect Infants Against Pertussis
The vaccine was 88% effective at preventing pertussis among infants younger than 2 months when administered during the third trimester of pregnancy.
FDA Grants Emergency Use Authorization to PCR Assay Test for Monkeypox Virus
The number of Mpox cases is expected to rise, which requires ongoing testing, vaccinations, and medication services by health care providers.
FDA Approves Tocilizumab as First Monoclonal Antibody Treatment of COVID-19
Intravenous tocilizumab (Actemra; Genentech) has been approved for the treatment of COVID-19 in individuals who are hospitalized and receiving systemic corticosteroids and supplemental oxygen.
Study Finds SARS-CoV-2 Booster Vaccination Lowers Infections, Hospitalizations, and Deaths in Nursing Homes
There are limited data on the efficacy of boosters for preventing infection and death in nursing home residents, but the findings suggest that boosters may have significantly reduced COVID-19–associated morbidity and mortality in this population.
FDA Authorizes Bivalent COVID-19 Vaccine Booster for Children 6 Months to 4 Years of Age
Booster shots updated for the Omicron variant BA.4 and BA.5 lineages cleared for children 6 months through 4 years of age.
Parents, Clinicians Can Take Steps to Manage Food Allergies During the Holidays
Parties and get-togethers often present challenges for patients with allergies, particularly with home-cooked food that may have unclear ingredients.
Data Analysis Shows Significant New Onset Morbidity Post-COVID-19 in Children, Adolescents, Adults
Although long-term health issues from COVID-19 are a major public health concern, evidence on post-COVID-19 symptoms are still limited, specifically among children and adolescents.
Study: Sedentary Lifestyle, Sugary Diet More Detrimental to Men
A feature of obesity and type 2 diabetes is vascular insulin, which contributes to vascular disease.
Counsel Patients About Pediatric Allergy Risks, Precautions On Halloween
Pharmacists can remind parents to have an EpiPen on hand and to carefully review candy after trick-or-treating.
Study: Children, Young Adults With Down Syndrome Have 4 Times Greater Chance of Diabetes
Investigators find that individuals aged 5 to 14 years with the genetic disorder are also at greater risk for TD2.
Research Suggests Gut Microbiome Impacts Brain Health, Dementia Risk
A Mediterranean-style diet appears to provide the greatest benefit to a healthy gut microbiome and brain.
Study: Depression Risk Rises With Hours Worked in Stressful Jobs
Data from a recent study show a clear need to further reduce the number of hours residents work each week on average to decrease the occurrence of depression.
De-Stigmatization of Sexual Assault May Contribute to Related Increase in Emergency Department Visits
Data show that an increase in sexual assault-related emergency department visits in 2019 may be due to social de-stigmatization of sexual assault during the #metoo movement of that year.