Hospital-Diagnosed Infections Associated With Increased Incidence of Dementia
Infections were associated with a 1.49-fold increase in the rate of dementia in both the short- and long-term rates, however, the increases were greater in the short term.
Significant Phase 2 Findings Support Zilebesiran as Anti-Hypertension Treatment
KARDIA-1 study met its primary and secondary endpoints, and the drug maintained a positive tolerability profile treating high systolic blood pressure.
Research Seeks to Aid Management of Type 2 Diabetes Through Dietary Education
An upcoming large-scale clinical trial of the Glucose Everyday Matters program will evaluate its safety and efficacy in managing type 2 diabetes.
Researchers Find Increased Risk of Atrial Fibrillation After Menopause
Stressful life events and poor sleeping patterns are linked to the development of atrial fibrillation in older women.
Novel Region in Human Genome in Those With African Ancestry Limits HIV Replication
After identifying the CHD1L gene, investigators explored the biological mechanism for the genetic association in those of African descent, determining the gene limits HIV replication in a subset of white blood cells.
mRNA-1273 Vaccine Associated With Lower Risk of Adverse Events, Likelihood of COVID-19 Diagnosis
Compared to the BNT162b2 vaccine, the mRNA-1273 vaccine was associated with a lower risk of adverse events, which investigators speculate was due to interrelated safety and efficacy.
Merck Announces Positive Results From Phase 3 Pneumococcal Vaccine Trials
If approved, the V116 vaccine would be the first pneumococcal conjugate vaccine specifically designed for adults.
Better Sleep Consolidation, Absence of Obstructive Sleep Apnea Are Associated With Better Cognition Over 5 Years of Follow-Up
Further research is necessary in order to investigate whether poor sleep can be a potential risk factor for dementia.
Immunoprophylaxis Guidance for RSV Not Aligned With Current Hospitalization Patterns, Study Finds
Investigators urge policymakers to establish flexible models that maximize coverage when respiratory syncytial virus activity is high and minimize unnecessary doses when viral activity is low.
American Diabetes Association, Abbott Announce Collaboration on Nutrition Program for Those with Diabetes
The collaboration will focus on engaging with health experts and opinion leaders to examine data to gain a better understanding of the role continuous glucose monitoring systems have in personalized therapeutic nutrition.
Multivitamin Supplementation May Be Linked With Improved Nutrition in Older Men
Multivitamins were associated with increased cellular oxygen consumption and more optimal blood nutrition biomarkers.
Point-of-Care Testing Shows Promise in Future, Concerns About Sensitivity Accuracy
The CDC has recommended a follow-up nucleic acid amplification test to be used for patients clinically suspected to have influenza, despite a negative POC test.
FDA Approves First Intravenous Iron Replacement Therapy for Adults With Heart Failure, Iron Deficiency
Treatment with Injectafer significantly improved exercise capacity compared to placebo in a randomized clinical trial in adult patients with heart failure.
Linked Immunization Information System, Claims Data Captured COVID-19 Vaccination Status Better Than Claims Data Alone
Reporting vaccination data to Immunization Information Systems databases can support public health surveillance activities.
Melatonin May Worsen Gut Inflammation in Patients With Irritable Bowel Diseases
The sleep hormone decreased intestinal homeostasis, which may augment inflammation that causes tissue and intestinal damage.
FDA Ends Ban on Blood Donations From Gay, Bisexual Men
A new FDA policy would assess blood donor eligibility using a set of individual risk-based questions to reduce the risk of transfusion-transmitted HIV.
Study: Unawareness of Memory Decline Associated With Future Progression in Older Adults
Lack of awareness, or anosognosia, may be present up to 2 to 3 years before an Alzheimer dementia diagnosis is made.
Monoclonal Antibody Combination Treatment Not Considered Significantly Effective Against COVID-19
Study shows intramuscular injection may improve treatment success by increasing the speed of drug absorption.
Study: Acute, Consistent Treatment With CBG Oil May Decrease Blood Pressure
For individuals with normal blood pressure, a sudden drop in blood pressure can be dangerous because it creates a lack of critical oxygen.
FDA Authorizes Changes to Simplify Use of Bivalent mRNA COVID-19 Vaccines
Agency updates emergency use authorization for the Moderna and Pfizer-BioNTech COVID-19 vaccinations, which are no longer authorized for used in the United States.
Study: Individuals With HIV Have Higher Risk of Depression, Suicide
The risk is particularly high in the first 2 years after an HIV diagnosis.
FDA Grants EUA for Vilobelimab for Treatment of Critically Ill Patients With COVID-19
This drug is the first to control complement factor C5a, which is a protein that plays a significant but potentially harmful role in the body's immune response.
FDA Approves Rezafungin Injection for the Treatment of Candidemia, Invasive Candidiasis
Rezafungin (Rezzayo; Cidara Therapeutics Inc, Melinta Therapeutics LLC) is the first new treatment option approved for individuals with candidemia and invasive candidiasis in more than a decade.
Study: Single Dose of Vaccine May Protect Older Adults from RSV-Related Infection
Findings from the ongoing Adult Respiratory Syncytial Virus phase 3 trial suggest RSVPreF3 OA vaccine is effective and safe for individuals aged 60 years and older.
Research Finds Impact of Chronic Pain on Daily Life is Biggest Threat to Mental Health
Persistently pursuing valued goals and adjusting those goals in response to setbacks or obstacles may help explain how some individuals with chronic pain maintain their mental wellbeing.
Experts Debate Approaches to Oral Anticoagulation After Ablation
Findings from the AFFIRM trial found increased risks after stopping oral anticoagulant therapy after rhythm control, and the same is true for stopping treatment with oral anticoagulants after successful ablation.
Is It Too Late to Get a Flu Shot?
Ideally, older patients receive vaccinations by October, but disease activity often peaks in February or March.
Convenience, Effectiveness Prove Significant Attributes in Vaccine Uptake Decisions
US adults have a slightly stronger preference for fewer adverse events in relation to pediatric COVID-19 vaccination, study results show.
Migraine Associated With Preterm Birth, Preeclampsia Complications During Pregnancy
Migraine could be considered a clinical marker of increased obstetric risk in pregnant women.
States With Legal Medical, Recreational Cannabis Policies Do Not Have Significantly Higher Rate of Psychosis-Related Outcomes
This is the largest known study to consider medical and recreational cannabis policies with US psychosis-related health care claims.
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